Youth nowadays face competitive and more complex labor market to the extent that a degree does not guarantee the transition to employment. This is the case for university graduates and even worse for the vulnerable marginalized youth groups. UPHLS focuses on entrepreneurship to enable the recipients not only to acquire the entrepreneurship skills, but also to encourage them to be entrepreneurs and to uplift their living conditions. The skills acquired enable the youth to assess the environment and identify business opportunities/ideas, they are able to determine the requirements to start up a business and begin to understand the importance of saving and reducing expenses. This concept is very challenging as there are many factors hindering its attainment such as youth who don’t have neither the capital nor the collateral. The Government of Rwanda is striving to create an environment conducive for entrepreneurship and to change the citizen mindsets from being job seekers to job creators and UPHLS couldn’t agree more ! Through the STARTUP program, UPHLS has been contributing to the youth beneficiaries’ micro businesses creation and growth. In the developing world, successful small businesses are the primary engines of job creation, income growth, and poverty reduction. For the last 3 years, 550 youth graduated from technical skills have been given startup toolkits to create their own small workshops and 900 youth were given support capital to start own micro businesses.